SCHEMBL8979446

SCHEMBL8979446

C=Cc1ccc([B-](c2ccc(C=C)cc2)(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)cc1.C[NH+](C)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8979448 0.97 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL8979464 0.89 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL8979449 0.85 TP53 (0.35) ALDH1A1TSHR
SCHEMBL8979454 0.85 ALDH1A1 (0.43) ALDH1A1TSHR
Trimethylammonium SCHEMBL8979528 0.83 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL8979443 0.82 TP53 (0.35) ALDH1A1TSHR
SCHEMBL7460569 0.81
SCHEMBL7455798 0.81
SCHEMBL21086754 0.79 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL116944 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0710663-A1 Boron-containing compound, its polymer, catalyst comprising the polymer and metallocene compound, and process for producing polyolefin Japan Polyolefins Co., Ltd. (JP) 1996-05-08 EP disclosed