Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979499 | 0.84 | ALOX5 (0.38) | ALOX5CYP11B1CYP11B2TRPV1 | |
| SCHEMBL8979493 | 0.83 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL8979505 | 0.82 | ALOX5 (0.50) | ALOX5CYP11B1CYP11B2 | |
| SCHEMBL2108127 | 0.77 | ALOX5 (0.39) | ALOX5CYP11B1CYP11B2TRPV1 | |
| SCHEMBL8979516 | 0.75 | ALOX5 (0.46) | ALOX5CYP11B1CYP11B2TRPV1 | |
| SCHEMBL8979482 | 0.74 | ALOX5 (0.34) | ALOX5CYP11B1CYP11B2 | |
| SCHEMBL8979495 | 0.73 | TRIM24 (0.35) | CYP11B1CYP11B2TRPV1 | |
| SCHEMBL8979554 | 0.71 | TRIM24 (0.38) | ALOX5CYP11B1CYP11B2TRPV1 | |
| SCHEMBL8979546 | 0.69 | TRIM24 (0.34) | ALOX5CYP11B1CYP11B2TRPV1CHRM1 | |
| SCHEMBL8979547 | 0.69 | ALOX5 (0.33) | ALOX5CYP11B1CYP11B2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512594-A | ADMINISTERING TO TREAT A MEDICAL CONDITION MEDIATED BY ONE OR MORE LEUKOTRIENES | ZENECA LIMITED (GB) | 1996-04-30 | — | — | US | disclosed |