SCHEMBL8979685

SCHEMBL8979685

C=C(CC(=O)OCc1ccccc1Br)C(=O)OCc1ccccc1Br

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
MAPT P10636 3/20 0.46
KMT2A Q03164 3/20 0.46
RAB9A P51151 2/20 0.46
POLB P06746 1/20 0.46
PKM P14618 1/20 0.46
MMP1 P03956 1/20 0.45
MMP2 P08253 1/20 0.45
MMP9 P14780 1/20 0.45
MMP12 P39900 1/20 0.45
IDO1 P14902 2/20 0.42
PARP10 Q53GL7 1/20 0.41
NPC1 O15118 1/20 0.40
TSHR P16473 2/20 0.39
FFAR4 Q5NUL3 2/20 0.39
FFAR1 O14842 1/20 0.39
RIPK1 Q13546 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9355221 0.93 ALDH1A1 (0.45) ALDH1A1MAPTKMT2ARAB9APOLB
SCHEMBL10800307 0.85 ALDH1A1 (0.56) ALDH1A1MAPTKMT2ARAB9APOLB
SCHEMBL7089127 0.82 POLB (0.48) ALDH1A1MAPTKMT2ARAB9APOLB
SCHEMBL10800311 0.81 ALDH1A1 (0.52) ALDH1A1MAPTKMT2ARAB9APOLB
SCHEMBL3290961 0.80 MAPT (0.52) ALDH1A1MAPTKMT2ARAB9APOLB
SCHEMBL20954406 0.80 MAPT (0.56) ALDH1A1MAPTKMT2ARAB9APOLB
SCHEMBL1683495 0.79 IDO1 (0.45) ALDH1A1MAPTKMT2ARAB9APOLB
SCHEMBL10660818 0.78 IDO1 (0.46) KMT2AIDO1FFAR4FFAR1
SCHEMBL27787123 0.78 ALDH1A1 (0.56) ALDH1A1MAPTKMT2ARAB9APOLB
SCHEMBL7086477 0.78 GAA (0.43) ALDH1A1MAPTRAB9ANPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0242618-B1 Transparent optical article and process for preparing same NIPPON OILS & FATS CO LTD (JP) 1994-11-02 EP claimed
US-5340893-A Blend containing an allyl containing polyester NOF CORPORATION (JP) 1994-08-23 US claimed
US-4948854-A COPOLYMER INCLUDING ITACONIC ACID DIESTER SEIKO EPSON CORPORATION (JP) 1990-08-14 US claimed
US-4930879-A Synthetic resin lens NIPPON OIL AND FATS CO., LTD. (JP) 1990-06-05 US claimed
EP-0242618-A2 Transparent optical article and process for preparing same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-10-28 EP claimed
EP-0540043-B1 Cast resin for optical use NOF CORP (JP) 1996-05-15 EP disclosed
EP-0242618-B1 Transparent optical article and process for preparing same NIPPON OILS & FATS CO LTD (JP) 1994-11-02 EP disclosed
US-5340893-A Blend containing an allyl containing polyester NOF CORPORATION (JP) 1994-08-23 US disclosed
EP-0540043-A1 Cast resin for optical use NOF CORPORATION (JP) 1993-05-05 EP disclosed
US-4948854-A COPOLYMER INCLUDING ITACONIC ACID DIESTER SEIKO EPSON CORPORATION (JP) 1990-08-14 US disclosed
US-4930879-A Synthetic resin lens NIPPON OIL AND FATS CO., LTD. (JP) 1990-06-05 US disclosed
EP-0242618-A2 Transparent optical article and process for preparing same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-10-28 EP disclosed