Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGT | P01019 | 2/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979788 | 0.90 | AGT (0.41) | AGTAGTR1AGTR2 | |
| SCHEMBL8979798 | 0.88 | AGT (0.40) | AGTAGTR1AGTR2 | |
| SCHEMBL8979868 | 0.88 | AGT (0.42) | AGTAGTR1AGTR2 | |
| SCHEMBL9237214 | 0.86 | AGTR1 (0.44) | AGTAGTR1AGTR2 | |
| SCHEMBL8979780 | 0.83 | — | — | |
| SCHEMBL8979874 | 0.83 | AGT (0.51) | AGTAGTR1AGTR2 | |
| SCHEMBL9268766 | 0.82 | AGT (0.38) | AGTAGTR1AGTR2 | |
| SCHEMBL9230545 | 0.81 | AGTR1 (0.40) | AGTAGTR1AGTR2 | |
| SCHEMBL9269303 | 0.77 | AGT (0.48) | AGTAGTR1AGTR2 | |
| SCHEMBL9235647 | 0.77 | AGTR1 (0.58) | AGTAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565464-A | Compounds having angiotensine II antagonistic activity | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1996-10-15 | — | — | US | disclosed |
| EP-0474817-B1 | BICYCLO [3.3.0]OCTANE DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR PHARMACEUTICAL USE | SCHERING AG (DE) | 1995-10-11 | — | — | EP | disclosed |
| EP-0641329-A1 | COMPOUNDS HAVING ANGIOTENSINE II ANTAGONISTIC ACTIVITY | ISTITUTO LUSO FARMACO D'ITALIA S.p.A. (IT) | 1995-03-08 | — | — | EP | disclosed |
| WO-1993003018-A1 | COMPOUNDS HAVING ANGIOTENSINE II ANTAGONISTIC ACTIVITY | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1993-02-18 | — | — | WO | disclosed |