Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2290951 | 0.89 | ATM (0.51) | ELANEATML3MBTL1CYP1A2MAPT | |
| SCHEMBL17354690 | 0.83 | ELANE (0.43) | ELANEATML3MBTL1CYP1A2MAPT | |
| SCHEMBL17617137 | 0.81 | ELANE (0.50) | ELANEATML3MBTL1CYP1A2MAPT | |
| SCHEMBL650639 | 0.81 | ELANE (0.50) | ELANEATML3MBTL1CYP1A2MAPT | |
| SCHEMBL14996055 | 0.81 | ELANE (0.50) | ELANEATML3MBTL1CYP1A2MAPT | |
| SCHEMBL2294888 | 0.81 | ATM (0.58) | ELANEATML3MBTL1CYP1A2MAPT | |
| SCHEMBL650209 | 0.79 | ATM (0.51) | ELANEATML3MBTL1CYP1A2MAPT | |
| SCHEMBL19105214 | 0.79 | ATM (0.51) | ELANEATML3MBTL1CYP1A2MAPT | |
| SCHEMBL2293834 | 0.79 | ATM (0.49) | ELANEATML3MBTL1CYP1A2MAPT | |
| SCHEMBL28445991 | 0.79 | ELANE (0.42) | ELANEATML3MBTL1CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563290-A | Method for preparing optically active succinic acid compound | NIPPON OIL CO. LTD. (JP) | 1996-10-08 | — | — | US | claimed |
| US-5563290-A | Method for preparing optically active succinic acid compound | NIPPON OIL CO. LTD. (JP) | 1996-10-08 | — | — | US | disclosed |
| EP-0663382-A1 | Process for preparing optically active succinic acid compound | NIPPON OIL CO. LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |