SCHEMBL2290951

SCHEMBL2290951

CCC(C(=O)Oc1ccccc1)C(C)C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
ELANE P08246 3/20 0.47
CYP1A2 P05177 1/20 0.46
MAPT P10636 3/20 0.43
TDP1 Q9NUW8 3/20 0.42
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
FFAR1 O14842 1/20 0.40
ALDH1A1 P00352 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
POLB P06746 1/20 0.40
MIF P14174 1/20 0.40
FAAH O00519 1/20 0.40
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8980199 0.89 ELANE (0.47) ATML3MBTL1ELANECYP1A2MAPT
SCHEMBL2293834 0.86 ATM (0.49) ATML3MBTL1ELANECYP1A2MAPT
SCHEMBL19573301 0.84 ATM (0.50) ATML3MBTL1ELANECYP1A2MAPT
SCHEMBL17354690 0.83 ELANE (0.43) ATML3MBTL1ELANECYP1A2MAPT
SCHEMBL2296074 0.83 ATM (0.46) ATML3MBTL1ELANETDP1ALDH1A1
SCHEMBL14996055 0.81 ELANE (0.50) ATML3MBTL1ELANECYP1A2MAPT
SCHEMBL650639 0.81 ELANE (0.50) ATML3MBTL1ELANECYP1A2MAPT
SCHEMBL17617137 0.81 ELANE (0.50) ATML3MBTL1ELANECYP1A2MAPT
SCHEMBL13924411 0.81 L3MBTL1 (0.55) ATML3MBTL1ELANECYP1A2MAPT
SCHEMBL29321235 0.81 ACHE (0.37) ATML3MBTL1ELANEMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4391827-A1 METHOD OF MITIGATING OFF-ODORS Givaudan SA (CH) 2024-07-03 EP claimed
US-20240197221-A1 FRAGRANCE FOR IMPROVING HAPPINESS STATE AND METHOD OF ASSESSING GIVAUDAN SA (CH) 2024-06-20 US claimed
EP-4347758-A1 FRAGRANCE FOR IMPROVING HAPPINESS STATE AND METHOD OF ASSESSING Givaudan SA (CH) 2024-04-10 EP claimed
US-20240000746-A1 New Cooling Agents and Preparations Containing Them SYMRISE AG (DE) 2024-01-04 US claimed
WO-2023168069-A1 FRAGRANCE COMPOSITIONS FOR SLEEP IMPROVEMENT INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2023-09-07 WO claimed
WO-2023025549-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2023-03-02 WO claimed
US-20200048578-A1 ORGANIC COMPOUNDS GIVAUDAN S.A. (CH) 2020-02-13 US claimed
US-20180051231-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2018-02-22 US claimed
EP-3271443-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS Givaudan SA (CH) 2018-01-24 EP claimed
WO-2016146673-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2016-09-22 WO claimed
EP-1490469-A2 METHODS AND COMPOSITIONS FOR REMOVING RESIDUES AND SUBSTANCES FROM SUBSTRATES USING ENVIRONMENTALLY FRIENDLY SOLVENTS North Carolina State University (US) 2004-12-29 EP claimed
US-20030213747-A1 Methods and compositions for removing residues and substances from substrates using environmentally friendly solvents NORTH CAROLINA STATE UNIVERSITY 2003-11-20 US claimed
WO-2003072215-A2 METHODS AND COMPOSITIONS FOR REMOVING RESIDUES AND SUBSTANCES FROM SUBSTRATES USING ENVIRONMENTALLY FRIENDLY SOLVENTS NORTH CAROLINA STATE UNIVERSITY (US) 2003-09-04 WO claimed
US-4332829-A Methylthiomethyl esters as flavor additives POLAK'S FRUTAL WORKS, B.V. (NL) 1982-06-01 US claimed
EP-4391827-A1 METHOD OF MITIGATING OFF-ODORS Givaudan SA (CH) 2024-07-03 EP disclosed
US-20240206778-A1 FRAGRANCE FOR IMPROVING INVIGORATION STATE AND METHOD OF ASSESSING GIVAUDAN SA (CH) 2024-06-27 US disclosed
US-20240197221-A1 FRAGRANCE FOR IMPROVING HAPPINESS STATE AND METHOD OF ASSESSING GIVAUDAN SA (CH) 2024-06-20 US disclosed
US-4067344-A Novel tobacco product comprising one or more thiazolines and process INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-01-10 US disclosed
US-3977419-A TOBACCO ARTICLE COMPRISING A FLAVORING COMPOSITION SELECTED FROM BUTANONE DERIVATIVES AND THE PROCESS FOR MAKING THE SAME INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-08-31 US disclosed
US-3977418-A TOBACCO ARTICLE COMPRISING THE FLAVORING COMPOSITION TRICYCLENE-9-BUTENONE AND THE PROCESS FOR MAKING THE SAME INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240000746-A1 New Cooling Agents and Preparations Containing Them TTPA, TREH, TAS2R45 ATM 3164/4885L3MBTL1 4713/4885ELANE 197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.