Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377256 | 0.97 | CA1 (0.58) | CA1CA2CA9CA7CA12 | |
| SCHEMBL3139320 | 0.95 | CA1 (0.55) | CA1CA2CA9CA7CA12 | |
| SCHEMBL12619982 | 0.82 | CA1 (0.41) | CA1CA2CA9CA7CA12 | |
| SCHEMBL12786310 | 0.82 | RXFP1 (0.59) | CA1CA2MAPK1ALDH1A1LMNA | |
| SCHEMBL13338785 | 0.79 | SLC2A1 (0.43) | CA1CA2CA9CA7CA12 | |
| SCHEMBL11604292 | 0.76 | ALDH1A1 (0.41) | CA1CA2CA9TDP1CYP3A4 | |
| SCHEMBL409015 | 0.74 | HDAC3 (0.32) | — | |
| 1,4-Dimethoxybenzene SCHEMBL21802643 | 0.74 | CA1 (1.00) | CA1CA2CA9CA7CA12 | |
| 1,4-Dimethoxybenzene SCHEMBL8489 | 0.74 | CA1 (1.00) | CA1CA2CA9CA7CA12 | |
| SCHEMBL16202955 | 0.74 | CA1 (0.61) | CA1CA2CA9CA7CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563290-A | Method for preparing optically active succinic acid compound | NIPPON OIL CO. LTD. (JP) | 1996-10-08 | — | — | US | claimed |
| US-5563290-A | Method for preparing optically active succinic acid compound | NIPPON OIL CO. LTD. (JP) | 1996-10-08 | — | — | US | disclosed |
| EP-0663382-A1 | Process for preparing optically active succinic acid compound | NIPPON OIL CO. LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |