SCHEMBL8980294

SCHEMBL8980294

COc1cc(O)c(OCc2ccccc2)cc1S(=O)(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.55
ALDH1A1 P00352 1/20 0.55
MAPT P10636 1/20 0.55
KMT2A Q03164 1/20 0.55
MAOB P27338 2/20 0.46
HPGD P15428 2/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
SMPD1 P17405 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
MRGPRX4 Q96LA9 2/20 0.45
RXRA P19793 1/20 0.45
ATM Q13315 1/20 0.44
ERN1 O75460 1/20 0.44
MPL P40238 1/20 0.43
ELANE P08246 1/20 0.43
CTSG P08311 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10344839 0.82 MAOB (0.43) LMNAALDH1A1MAPTKMT2AMAOB
SCHEMBL10344838 0.81 MAOB (0.48) LMNAMAOBHPGDHDAC6
SCHEMBL9141423 0.80 KMT2A (0.60) LMNAALDH1A1MAPTKMT2AHPGD
SCHEMBL7353198 0.80 MAOB (0.51) LMNAALDH1A1MAPTMAOBHPGD
SCHEMBL8980297 0.79 KMT2A (0.59) LMNAALDH1A1MAPTKMT2AHPGD
SCHEMBL11163647 0.79 LMNA (0.55) LMNAMAPTMAOBHPGDHDAC6
SCHEMBL344641 0.79 ELANE (0.49) LMNAMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL8663594 0.78 MAOB (0.50) LMNAALDH1A1MAPTMAOBHPGD
SCHEMBL8650450 0.76 MAPT (0.62) LMNAALDH1A1MAPTKMT2AHPGD
SCHEMBL1028419 0.75 ALPG (0.51) MAPTNPC1RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0591786-B1 Photosensitive composition FUJI PHOTO FILM CO LTD (JP) 1996-05-15 EP disclosed
EP-0591786-A2 Photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1994-04-13 EP disclosed