Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | CDC25B | P30305 | 1/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BUB1 | O43683 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3142790 | 0.86 | LMNA (0.63) | LMNAPTPN1CDC25BAKT1L3MBTL1 | |
| SCHEMBL25307508 | 0.82 | LMNA (0.55) | LMNAPTPN1CDC25BAKT1L3MBTL1 | |
| SCHEMBL25307505 | 0.82 | LMNA (0.55) | LMNAPTPN1CDC25BAKT1L3MBTL1 | |
| SCHEMBL4794721 | 0.79 | LMNA (0.58) | LMNAPTPN1CDC25BAKT1L3MBTL1 | |
| SCHEMBL5237882 | 0.79 | LMNA (0.58) | LMNAPTPN1CDC25BAKT1L3MBTL1 | |
| SCHEMBL1335990 | 0.79 | LMNA (0.58) | LMNAPTPN1CDC25BAKT1L3MBTL1 | |
| SCHEMBL9267781 | 0.78 | LMNA (0.55) | LMNAPTPN1CDC25BAKT1 | |
| SCHEMBL6282511 | 0.78 | LMNA (0.55) | LMNAPTPN1CDC25BAKT1 | |
| SCHEMBL7080429 | 0.77 | CYP3A4 (0.54) | — | |
| SCHEMBL5671815 | 0.77 | CYP3A4 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504056-A | Heterocyclic cyclohexanedione derivative, production thereof, and herbicide | NIPPON SODA CO., LTD. (JP) | 1996-04-02 | — | — | US | disclosed |
| EP-0641780-A1 | HETEROCYCLIC CYCLOHEXANEDIONE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE | NIPPON SODA CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |