SCHEMBL8980767

SCHEMBL8980767

CCCCCCCCCCN(C)CCCC

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.63
S1PR2 O95136 1/20 0.58
S1PR1 P21453 1/20 0.58
S1PR3 Q99500 1/20 0.58
S1PR5 Q9H228 1/20 0.58
CHRM2 P08172 1/20 0.52
TSHR P16473 1/20 0.50
THRB P10828 1/20 0.50
GGPS1 O95749 4/20 0.48
KDM4C Q9H3R0 4/20 0.47
KDM5A P29375 3/20 0.47
PHF8 Q9UPP1 2/20 0.47
KDM4A O75164 1/20 0.47
FDPS P14324 1/20 0.47
AGTR1 P30556 1/20 0.47
OPRM1 P35372 1/20 0.47
PDE3A Q14432 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15236225 1.00 DNM1 (0.63) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL4687503 1.00 DNM1 (0.63) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL4952272 1.00 DNM1 (0.63) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL8980674 1.00 DNM1 (0.63) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL8980557 1.00 DNM1 (0.63) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL8980621 1.00 DNM1 (0.63) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL20345235 1.00 DNM1 (0.63) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL8980627 1.00 DNM1 (0.63) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL8980618 1.00 DNM1 (0.63) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL12462786 1.00 DNM1 (0.63) DNM1S1PR2S1PR1S1PR3S1PR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170362283-A1 NISIN-BASED COMPOUNDS AND USE THEREOF IN THE TREATMENT OF BACTERIAL INFECTIONS UNIVERSITEIT UTRECHT HOLDING B.V. (NL) 2017-12-21 US disclosed
EP-3060634-A1 USE OF AN ALKOXYLATED POLYTETRAHYDROFURAN AS AN ADDITIVE IN A FUEL BASF SE (DE) 2016-08-31 EP disclosed
EP-3060637-A2 USE OF A POLYALKYLENE GLYCOL TO REDUCE FUEL CONSUMPTION BASF SE (DE) 2016-08-31 EP disclosed
EP-3060636-A2 USE OF A COMPLEX ESTER TO REDUCE FUEL CONSUMPTION BASF SE (DE) 2016-08-31 EP disclosed
WO-2015058992-A1 USE OF AN ALKOXYLATED POLYTETRAHYDROFURAN AS AN ADDITIVE IN A FUEL BASF SE (DE) 2015-04-30 WO disclosed
WO-2015059063-A2 USE OF A COMPLEX ESTER TO REDUCE FUEL CONSUMPTION BASF SE (DE) 2015-04-30 WO disclosed
WO-2015058993-A2 USE OF A POLYALKYLENE GLYCOL TO REDUCE FUEL CONSUMPTION BASF SE (DE) 2015-04-30 WO disclosed
WO-2014023853-A2 TERTIARY AMINES FOR REDUCING INJECTOR NOZZLE FOULING AND MODIFYING FRICTION IN DIRECT INJECTION SPARK IGNITION ENGINES BASF SE (DE) 2014-02-13 WO disclosed
US-5536425-A DURABILITY SONY CORPORATION (JP) 1996-07-16 US disclosed
US-5453539-A Durability SONY CORPORATION (JP) 1995-09-26 US disclosed
EP-0519406-A2 Novel perfluoropolyether derivatives, and lubricants and magnetic recording medium using the same SONY CORPORATION (JP) 1992-12-23 EP disclosed
US-4138437-A REACTING ALCOHOL OR ALDEHYDE WITH DIMETHYLAMINE IN THE PRESENCE OF COPPER-CHROMIUM OXIDE CATALYST AND HYDROGEN HOECHST AKTIENGESELLSCHAFT (DE) 1979-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170362283-A1 NISIN-BASED COMPOUNDS AND USE THEREOF IN THE TREATMENT OF BACTERIAL INFECTIONS NISCH, VIP, NGLY1 DNM1 2153/4885S1PR2 2614/4885S1PR1 2196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.