Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 13/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733551 | 0.87 | TBXA2R (0.61) | TBXA2RTHRBMEN1KMT2ALMNA | |
| SCHEMBL8730147 | 0.86 | TBXA2R (0.64) | TBXA2RMEN1KMT2A | |
| SCHEMBL8731635 | 0.85 | TBXA2R (0.63) | TBXA2RTHRBMEN1KMT2ALMNA | |
| SCHEMBL8757853 | 0.83 | TBXA2R (0.61) | TBXA2RTHRBMEN1KMT2ALMNA | |
| SCHEMBL8733698 | 0.83 | TBXA2R (0.59) | TBXA2RTHRBMEN1KMT2ALMNA | |
| SCHEMBL8733700 | 0.82 | TBXA2R (0.62) | TBXA2RMEN1KMT2A | |
| SCHEMBL8758393 | 0.82 | TBXA2R (0.62) | TBXA2RMEN1KMT2A | |
| SCHEMBL8731665 | 0.82 | TBXA2R (0.57) | TBXA2RTHRBMEN1KMT2ALMNA | |
| SCHEMBL8730097 | 0.79 | TBXA2R (0.59) | TBXA2RMEN1KMT2ALMNA | |
| SCHEMBL8757844 | 0.79 | TBXA2R (0.67) | TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589037-B1 | INDIAN DERIVATIVE AND THROMBOXANE ANTAGONIST CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 1996-05-29 | — | — | EP | disclosed |
| US-5409956-A | A sulfonylaminoalkylindan carboxylic acid or ester for treating thrombosis, vasospasm or asthma | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0589037-A1 | INDIAN DERIVATIVE AND THROMBOXANE ANTAGONIST CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-30 | — | — | EP | disclosed |