Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 13/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733698 | 0.94 | TBXA2R (0.59) | TBXA2RTHRBLMNAMEN1KMT2A | |
| SCHEMBL8733551 | 0.90 | TBXA2R (0.61) | TBXA2RTHRBLMNAMEN1KMT2A | |
| SCHEMBL8731652 | 0.89 | TBXA2R (0.55) | TBXA2RTHRBLMNAMEN1KMT2A | |
| SCHEMBL8733700 | 0.87 | TBXA2R (0.62) | TBXA2RMEN1KMT2A | |
| SCHEMBL8733775 | 0.86 | TBXA2R (0.57) | TBXA2RMEN1KMT2A | |
| SCHEMBL8730097 | 0.84 | TBXA2R (0.59) | TBXA2RLMNAMEN1KMT2A | |
| SCHEMBL8731635 | 0.84 | TBXA2R (0.63) | TBXA2RTHRBLMNAMEN1KMT2A | |
| SCHEMBL8730147 | 0.83 | TBXA2R (0.64) | TBXA2RMEN1KMT2A | |
| SCHEMBL8982185 | 0.82 | TBXA2R (0.58) | TBXA2RTHRBLMNAMEN1KMT2A | |
| SCHEMBL8982168 | 0.81 | TBXA2R (0.58) | TBXA2RMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750524-A | ADMINISTERING AN SULFAMIDE SUBSTITUTED INDAN DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |