Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 2/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10799859 | 0.95 | CYP2C9 (0.40) | CYP2C9MAPTALDH1A1HTTSIGMAR1 | |
| SCHEMBL11044116 | 0.95 | CYP2C9 (0.40) | CYP2C9MAPTALDH1A1HTTSIGMAR1 | |
| SCHEMBL11044114 | 0.95 | CYP2C9 (0.40) | CYP2C9MAPTALDH1A1HTTSIGMAR1 | |
| SCHEMBL11312998 | 0.89 | ALDH1A1 (0.44) | MAPTALDH1A1HTTSIGMAR1SCN1A | |
| SCHEMBL10725865 | 0.89 | CYP2C9 (0.52) | CYP2C9MAPTALDH1A1LMNASCN1A | |
| SCHEMBL10725879 | 0.89 | CYP2C9 (0.52) | CYP2C9MAPTALDH1A1LMNASCN1A | |
| SCHEMBL11406713 | 0.88 | ALDH1A1 (0.43) | MAPTALDH1A1HTTSIGMAR1SCN1A | |
| SCHEMBL13135352 | 0.88 | CYP2C9 (0.51) | CYP2C9MAPTALDH1A1HTTLMNA | |
| SCHEMBL11038890 | 0.87 | ALDH1A1 (0.42) | MAPTALDH1A1HTTSIGMAR1SCN1A | |
| SCHEMBL11038892 | 0.87 | ALDH1A1 (0.42) | MAPTALDH1A1HTTSIGMAR1SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5518653-A | LIQUID CRYSTAL | HOFFMANN-LA ROCHE INC. (US) | 1996-05-21 | — | — | US | disclosed |