Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7072314 | 0.79 | CYP3A4 (0.50) | ALDH1A1DHFRFBP1KDM4EMEN1 | |
| SCHEMBL9171200 | 0.77 | CXCL12 (0.37) | NOTUMALDH1A1KDM4E | |
| SCHEMBL10395372 | 0.76 | GRM5 (0.51) | HAO1ALDH1A1PTGIRCHRNA7GRM5 | |
| SCHEMBL9376880 | 0.74 | PDE2A (0.39) | ALDH1A1 | |
| SCHEMBL2417142 | 0.73 | HAO1 (0.53) | HAO1NOTUMALDH1A1PTGIRGRM5 | |
| SCHEMBL11731364 | 0.71 | NR4A1 (0.32) | MEN1KMT2A | |
| Fluoride SCHEMBL29094698 | 0.71 | HAO1 (0.52) | HAO1NOTUMALDH1A1PTGIRGRM5 | |
| SCHEMBL2443970 | 0.70 | KIF11 (0.45) | NOTUMKIF11RAB9AKDM4ENPC1 | |
| SCHEMBL23366507 | 0.70 | HAO1 (0.49) | HAO1DHFRRAB9ATYMSKDM4E | |
| SCHEMBL4704621 | 0.69 | KIF11 (0.64) | HAO1ALDH1A1PTGIRDHFRKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527818-A | Sulfamoyltriazole derivatives of fungicidal composition containing same as effective component thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-06-18 | — | — | US | disclosed |
| EP-0603415-A1 | SULFAMOYLTRIAZOLE DERIVATIVE AND BACTERICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | MITSUBISHI CHEMICAL CORPORATION (JP) | 1994-06-29 | — | — | EP | disclosed |