SCHEMBL8983185

SCHEMBL8983185

O=S(=O)(O)c1ccccc1OOc1ccccc1S(=O)(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.42
TSHR P16473 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ELANE P08246 1/20 0.42
TTR P02766 2/20 0.41
HTR6 P50406 1/20 0.39
FABP4 P15090 2/20 0.37
CCNA2 P20248 1/20 0.37
CDK2 P24941 1/20 0.37
MAPK14 Q16539 1/20 0.37
NR4A1 P22736 1/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PGAM1 P18669 1/20 0.35
CYP1A2 P05177 2/20 0.35
GAA P10253 2/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5698446 0.86 MYC (0.42) MYCTSHRSMN1; SMN2ELANETTR
SCHEMBL9312072 0.84 MYC (0.40) MYCTSHRSMN1; SMN2ELANETTR
SCHEMBL4962913 0.84 MYC (0.41) MYCTSHRSMN1; SMN2ELANETTR
SCHEMBL28521154 0.84 MYC (0.41) MYCTSHRSMN1; SMN2ELANETTR
SCHEMBL6160456 0.84 SMN1; SMN2 (0.46) MYCTSHRSMN1; SMN2ELANETTR
SCHEMBL27855383 0.82 MYC (0.39) MYCTSHRSMN1; SMN2ELANETTR
SCHEMBL3139925 0.82 MYC (0.39) MYCTSHRSMN1; SMN2ELANETTR
SCHEMBL286480 0.82 HTR6 (0.60) MYCTSHRHTR6FABP4KMT2A
SCHEMBL8983201 0.82 ELANE (0.39) MYCTSHRSMN1; SMN2ELANETTR
SCHEMBL8363338 0.82 MYC (0.44) MYCTSHRSMN1; SMN2ELANETTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0474075-B1 Aromatic condensation products BAYER AG (DE) 1996-06-05 EP claimed
EP-0474075-A2 Aromatic condensation products BAYER AG (DE) 1992-03-11 EP claimed
EP-0474075-B1 Aromatic condensation products BAYER AG (DE) 1996-06-05 EP disclosed
EP-0474075-A2 Aromatic condensation products BAYER AG (DE) 1992-03-11 EP disclosed