Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8983428 | 0.80 | — | — | |
| SCHEMBL9790361 | 0.70 | ESR2 (0.30) | — | |
| SCHEMBL4501455 | 0.69 | OPRL1 (0.35) | — | |
| SCHEMBL29791605 | 0.67 | HTR2C (0.46) | HTR2AHTR2CHTR2B | |
| SCHEMBL18440305 | 0.67 | HTR2C (0.46) | HTR2AHTR2CHTR2B | |
| SCHEMBL13727914 | 0.67 | GRIA1 (0.40) | — | |
| SCHEMBL6988274 | 0.67 | — | — | |
| SCHEMBL261440 | 0.66 | MAPT (0.45) | — | |
| SCHEMBL21585257 | 0.62 | IL1RN (0.31) | — | |
| SCHEMBL29054978 | 0.61 | GRIA1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444853-B1 | Hexahydrobenz[cd]indoles | LILLY CO ELI (US) | 1996-06-05 | — | — | EP | disclosed |
| EP-0444853-A2 | Hexahydrobenz[cd]indoles | ELI LILLY AND COMPANY (US) | 1991-09-04 | — | — | EP | disclosed |
| US-5039820-A | Nervous system disorders | ELI LILLY AND COMPANY (US) | 1991-08-13 | — | — | US | disclosed |