Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.31 |
| ▸ | IL1RN | P18510 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4845544 | 0.67 | IL1RN (0.33) | IL1RNERAP2ERAP1 | |
| SCHEMBL24317394 | 0.65 | HTR2A (0.31) | IL1RNERAP2ERAP1 | |
| SCHEMBL8983390 | 0.61 | HTR2A (0.30) | — | |
| SCHEMBL13727914 | 0.61 | GRIA1 (0.40) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL9816066 | 0.60 | GRIA1 (0.45) | GRIA1GRIA2GRIA3GRIA4PARP10 | |
| SCHEMBL13249026 | 0.59 | HTR2C (0.40) | PARP10PARP11IL1RNERAP2ERAP1 | |
| SCHEMBL10463782 | 0.59 | HTR2C (0.40) | PARP10PARP11IL1RNERAP2ERAP1 | |
| SCHEMBL30509287 | 0.59 | HTR2C (0.40) | PARP10PARP11IL1RNERAP2ERAP1 | |
| SCHEMBL31731343 | 0.59 | ALDH1A1 (0.39) | GRIA1GRIA2GRIA3GRIA4PARP10 | |
| SCHEMBL28382169 | 0.58 | MAPT (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116723839-A | Tricyclic heterobifunctional compounds for degrading target proteins | C4医药公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-116457339-A | Tricyclic compounds degrading novel substrates for medical treatment | C4医药公司 | 2023-07-18 | — | — | CN | disclosed |