Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYNJ2 | O15056 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | ALPL | P05186 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ALPI | P09923 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALPG | P10696 | 1/20 | 0.57 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | GALK1 | P51570 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.57 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20281100 | 0.86 | SYNJ2 (0.56) | SYNJ2GAAKDM4EABL1ALPL | |
| SCHEMBL6067742 | 0.86 | SYNJ2 (0.56) | SYNJ2GAAKDM4EABL1ALPL | |
| SCHEMBL20276378 | 0.86 | SYNJ2 (0.56) | SYNJ2GAAKDM4EABL1ALPL | |
| SCHEMBL20276354 | 0.86 | SYNJ2 (0.56) | SYNJ2GAAKDM4EABL1ALPL | |
| SCHEMBL6067930 | 0.86 | SYNJ2 (0.56) | SYNJ2GAAKDM4EABL1ALPL | |
| SCHEMBL20276320 | 0.86 | SYNJ2 (0.56) | SYNJ2GAAKDM4EABL1ALPL | |
| SCHEMBL30834820 | 0.86 | SYNJ2 (0.56) | SYNJ2GAAKDM4EABL1ALPL | |
| SCHEMBL20265982 | 0.86 | SYNJ2 (0.56) | SYNJ2GAAKDM4EABL1ALPL | |
| SCHEMBL20281079 | 0.86 | SYNJ2 (0.56) | SYNJ2GAAKDM4EABL1ALPL | |
| SCHEMBL26304767 | 0.86 | SYNJ2 (0.56) | SYNJ2GAAKDM4EABL1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714405-A1 | THERAPEUTIC AND DIAGNOSTIC AGENTS FOR AMYLOIDOSIS | ROYAL POSTGRADUATE MEDICAL SCHOOL (GB) | 1996-06-05 | — | — | EP | claimed |