Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10845107 | 1.00 | CYP2D6 (0.71) | CYP2D6TSHRMAPK1KDM4EALDH1A1 | |
| SCHEMBL10845287 | 1.00 | CYP2D6 (0.71) | CYP2D6TSHRMAPK1KDM4EALDH1A1 | |
| SCHEMBL29630319 | 1.00 | CYP2D6 (0.71) | CYP2D6TSHRMAPK1KDM4EALDH1A1 | |
| SCHEMBL4179880 | 1.00 | CYP2D6 (0.71) | CYP2D6TSHRMAPK1KDM4EALDH1A1 | |
| SCHEMBL10845109 | 1.00 | CYP2D6 (0.71) | CYP2D6TSHRMAPK1KDM4EALDH1A1 | |
| SCHEMBL8317770 | 1.00 | CYP2D6 (0.71) | CYP2D6TSHRMAPK1KDM4EALDH1A1 | |
| SCHEMBL2723896 | 0.90 | CYP2D6 (0.75) | CYP2D6TSHRMAPK1KDM4EALDH1A1 | |
| SCHEMBL10846857 | 0.90 | CYP2D6 (0.75) | CYP2D6TSHRMAPK1KDM4EALDH1A1 | |
| SCHEMBL10846851 | 0.90 | CYP2D6 (0.75) | CYP2D6TSHRMAPK1KDM4EALDH1A1 | |
| SCHEMBL10843818 | 0.90 | CYP2D6 (0.75) | CYP2D6TSHRMAPK1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503044-B1 | PEPTIDE COMPOUNDS OF LAEVOROTATORY AMINO ACIDS AND RING MOLECULES, AND THERAPEUTICAL APPLICATIONS THEREOF | POLIFARMA SPA (IT) | 1996-06-12 | — | — | EP | disclosed |
| EP-0503044-A1 | PEPTIDE COMPOUNDS OF LAEVOROTATORY AMINO ACIDS AND RING MOLECULES, AND THERAPEUTICAL APPLICATIONS THEREOF. | POLIFARMA SPA (IT) | 1992-09-16 | — | — | EP | disclosed |
| WO-1992006108-A1 | PEPTIDE COMPOUNDS OF LAEVOROTATORY AMINO ACIDS AND RING MOLECULES, AND THERAPEUTICAL APPLICATIONS THEREOF | POLIFARMA S.P.A. (IT) | 1992-04-16 | — | — | WO | disclosed |