Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.66 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.66 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14218498 | 0.89 | ANPEP (0.65) | ANPEPERAP2DNM1CHRM2ALDH1A1 | |
| SCHEMBL6492794 | 0.84 | ANPEP (0.59) | ANPEPERAP2DNM1CHRM2ALDH1A1 | |
| SCHEMBL6499108 | 0.84 | ANPEP (0.59) | ANPEPERAP2DNM1CHRM2ALDH1A1 | |
| SCHEMBL15819968 | 0.84 | ANPEP (0.59) | ANPEPERAP2DNM1CHRM2ALDH1A1 | |
| SCHEMBL17504540 | 0.84 | ANPEP (0.63) | ANPEPERAP2DNM1CHRM2ALDH1A1 | |
| SCHEMBL21245400 | 0.84 | ANPEP (0.63) | ANPEPERAP2DNM1CHRM2ALDH1A1 | |
| SCHEMBL3680963 | 0.81 | DNM1 (0.59) | ANPEPERAP2DNM1CHRM2ALDH1A1 | |
| SCHEMBL23367774 | 0.80 | ANPEP (0.58) | ANPEPERAP2DNM1CHRM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10276533 | 0.80 | ANPEP (0.58) | ANPEPERAP2DNM1CHRM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10276301 | 0.80 | ANPEP (0.58) | ANPEPERAP2DNM1CHRM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012042534-A2 | PROCESSES FOR THE PREPARATION OF R-SITAGLIPTIN AND INTERMEDIATES THEREOF | GLENMARK GENERICS LIMITED (IN) | 2012-04-05 | — | — | WO | claimed |
| WO-2012042534-A2 | PROCESSES FOR THE PREPARATION OF R-SITAGLIPTIN AND INTERMEDIATES THEREOF | GLENMARK GENERICS LIMITED (IN) | 2012-04-05 | — | — | WO | disclosed |