Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 5/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21517561 | 0.97 | PDK2 (0.48) | PDK2CA12CA9ABCC9CYP2A6 | |
| SCHEMBL30807392 | 0.91 | PDK2 (0.51) | PDK2CA12CA9ABCC9CYP2A6 | |
| SCHEMBL25883203 | 0.88 | PDK2 (0.41) | PDK2ABCC9 | |
| SCHEMBL30617898 | 0.87 | PDK2 (0.50) | PDK2CA12CA9ABCC9CYP2A6 | |
| SCHEMBL17614576 | 0.87 | PDK2 (0.50) | PDK2CA12CA9ABCC9CYP2A6 | |
| SCHEMBL23257085 | 0.87 | PDK2 (0.43) | PDK2ABCC9 | |
| SCHEMBL21517355 | 0.87 | PDK2 (0.43) | PDK2ABCC9 | |
| SCHEMBL20618987 | 0.86 | PDK2 (0.52) | PDK2PGR | |
| SCHEMBL19299175 | 0.86 | PDK2 (0.52) | PDK2PGR | |
| SCHEMBL21701669 | 0.85 | PDK2 (0.40) | PDK2ABCC9ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578737-A | SUBSTITUTED FLUORENES, MONOMERS FOR HIGH PERFORMANCE POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1996-11-26 | — | — | US | claimed |
| US-5578737-A | SUBSTITUTED FLUORENES, MONOMERS FOR HIGH PERFORMANCE POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1996-11-26 | — | — | US | disclosed |
| US-5387725-A | Chlorinating compounds having acidic protons with a perchloro-alkane and aqueous base in the presence of a tetraalkyl-ammonium hydroxide phase transfer catalyst | THE DOW CHEMICAL COMPANY (US) | 1995-02-07 | — | — | US | disclosed |
| WO-1993009074-A2 | CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1993-05-13 | — | — | WO | disclosed |