SCHEMBL19299175

SCHEMBL19299175

N#Cc1ccc(-c2ccc(-c3ccc4c(c3)C3(c5ccccc5O4)c4ccccc4-c4ccccc43)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 5/20 0.52
OPRD1 P41143 1/20 0.38
BACE1 P56817 1/20 0.37
KCNH2 Q12809 1/20 0.37
MAOB P27338 1/20 0.36
PGR P06401 3/20 0.36
GABRA1 P14867 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36
MYC P01106 1/20 0.34
MMP3 P08254 1/20 0.33
KAT6A Q92794 1/20 0.33
MAP4K4 O95819 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20618987 1.00 PDK2 (0.52) PDK2OPRD1BACE1KCNH2MAOB
SCHEMBL20619346 0.96 PDK2 (0.49) PDK2OPRD1BACE1KCNH2MAOB
SCHEMBL20222614 0.93 PDK2 (0.54) PDK2OPRD1BACE1KCNH2MAOB
SCHEMBL20619779 0.92 PDK2 (0.44) PDK2OPRD1BACE1KCNH2MAOB
SCHEMBL20222787 0.92 PDK2 (0.55) PDK2OPRD1BACE1KCNH2MAOB
SCHEMBL19298647 0.92 PDK2 (0.49) PDK2OPRD1BACE1KCNH2MAOB
SCHEMBL20619231 0.92 PDK2 (0.49) PDK2OPRD1BACE1KCNH2MAOB
SCHEMBL29808802 0.92 PDK2 (0.54) PDK2OPRD1MAOBPGRGABRA1
SCHEMBL20619113 0.91 PDK2 (0.53) PDK2MAOBPGRGABRA1GABRG2
SCHEMBL22484422 0.91 PDK2 (0.47) PDK2OPRD1BACE1KCNH2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024114-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2023-01-26 US disclosed
US-20220376178-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2022-11-24 US disclosed
US-11152576-B2 Organic light emitting device LG CHEM, LTD. (KR) 2021-10-19 US disclosed
US-20210288264-A1 Heterocyclic Compound And Organic Light Emitting Element Comprising Same LG CHEM, LTD. (KR) 2021-09-16 US disclosed
US-11094889-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. 2021-08-17 US disclosed
US-20210013422-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2021-01-14 US disclosed
EP-3595025-B1 ORGANIC LIGHT EMITTING ELEMENT LG CHEMICAL LTD (KR) 2020-12-30 EP disclosed
US-20200365814-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2020-11-19 US disclosed
US-20200035930-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-01-30 US disclosed
WO-2019004782-A1 ORGANIC LIGHT EMITTING ELEMENT 주식회사 엘지화학 2019-01-03 WO disclosed
WO-2019004787-A1 ORGANIC LIGHT EMITTING ELEMENT 주식회사 엘지화학 2019-01-03 WO disclosed
WO-2017146466-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2017-08-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210288264-A1 Heterocyclic Compound And Organic Light Emitting Element Comprising Same CRY1, CRY2, PER2 PDK2 2812/4885OPRD1 826/4885BACE1 616/4885
US-11094889-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, PER2 PDK2 2812/4885OPRD1 826/4885BACE1 616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.