Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.47 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007652 | 0.83 | MAPT (0.61) | GPR183KMT2AMEN1BCHEHTR2C | |
| SCHEMBL9410731 | 0.83 | GPR183 (0.56) | GPR183KMT2AMEN1BCHEHTR2C | |
| SCHEMBL9229969 | 0.82 | HSD11B1 (0.62) | GPR183KMT2AMEN1GFERATM | |
| Hydrochloric Acid SCHEMBL7620223 | 0.82 | MAPT (0.59) | GPR183KMT2AMEN1BCHEHTR2C | |
| SCHEMBL14198735 | 0.81 | SLC6A4 (0.56) | GPR183KMT2AMEN1BCHEHTR2C | |
| SCHEMBL16578041 | 0.81 | HSD11B1 (0.69) | GPR183KMT2AMEN1SMN1; SMN2SIGMAR1 | |
| SCHEMBL18195121 | 0.80 | GPR183 (0.53) | GPR183KMT2AMEN1BCHEHTR2C | |
| SCHEMBL8984809 | 0.75 | KMT2A (0.64) | KMT2AMEN1BCHEPKMRAB9A | |
| SCHEMBL8984761 | 0.75 | HDAC3 (0.47) | HDAC3HDAC1HDAC2HDAC6SMN1; SMN2 | |
| SCHEMBL16002918 | 0.75 | HDAC3 (0.55) | GPR183KMT2AMEN1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714909-A1 | Composition for prophylaxis or treatment of pulmonary circulatory diseases | Takeda Chemical Industries, Ltd. (JP) | 1996-06-05 | — | — | EP | disclosed |
| EP-0647449-A1 | Sustained-release preparation of anti-endothelin substance | Takeda Chemical Industries, Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |