Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.60 |
| ▸ | THRB | P10828 | 3/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.44 |
| ▸ | SRC | P12931 | 3/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9362335 | 0.94 | THRA (0.54) | THRATHRBS1PR1MEN1KMT2A | |
| SCHEMBL8984900 | 0.92 | THRA (0.51) | THRATHRBS1PR1MEN1KMT2A | |
| SCHEMBL1013811 | 0.92 | THRA (0.54) | THRATHRBS1PR1MEN1KMT2A | |
| SCHEMBL7725119 | 0.90 | THRA (0.52) | THRATHRBS1PR1FFAR1FFAR4 | |
| SCHEMBL7735134 | 0.90 | THRA (0.52) | THRATHRBS1PR1MEN1KMT2A | |
| SCHEMBL3682530 | 0.88 | THRA (0.48) | THRATHRBS1PR1FFAR1FFAR4 | |
| SCHEMBL3684301 | 0.87 | THRA (0.71) | THRATHRBS1PR1MEN1KMT2A | |
| SCHEMBL7735332 | 0.87 | FFAR1 (0.51) | THRATHRBS1PR1MEN1KMT2A | |
| SCHEMBL3888439 | 0.86 | FFAR4 (0.54) | THRATHRBS1PR1FFAR1FFAR4 | |
| SCHEMBL3885965 | 0.85 | THRA (0.50) | THRATHRBS1PR1FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473308-B1 | Aldose reductase inhibitor | ASAHI CHEMICAL IND (JP) | 1996-05-22 | — | — | EP | disclosed |
| US-5155259-A | High stability; prevention and therapy of diabetic complications | TOYO JOZO KABUSHIKI KAISHA (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0473308-A1 | Aldose reductase inhibitor | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1992-03-04 | — | — | EP | disclosed |