SCHEMBL8985148

SCHEMBL8985148

N#CNc1ccc(C(c2ccccc2)c2ccc(NC#N)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C1 Q04828 1/20 0.41
SLC6A2 P23975 4/20 0.40
SLC6A4 P31645 3/20 0.40
SLC6A3 Q01959 3/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
TSHR P16473 3/20 0.39
TRPA1 O75762 1/20 0.39
CYP19A1 P11511 2/20 0.37
CFTR P13569 1/20 0.36
GOPC Q9HD26 1/20 0.36
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
HTR2A P28223 1/20 0.32
HRH1 P35367 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11505453 0.91 CYP19A1 (0.36) ALDH1A1AKR1C3AKR1C1CYP19A1GAA
Water SCHEMBL11606806 0.79 ALDH1A1 (0.45) ALDH1A1SLC6A2TSHRMEN1KMT2A
Water SCHEMBL11606809 0.79 ALDH1A1 (0.45) ALDH1A1SLC6A2TSHRMEN1KMT2A
Benzene SCHEMBL28295973 0.79 ALDH1A1 (0.45) ALDH1A1SLC6A2TSHRMEN1KMT2A
SCHEMBL1259441 0.79
SCHEMBL28530865 0.77 ALDH1A1 (0.43) ALDH1A1SLC6A2TSHRMEN1KMT2A
Hydrogen Sulfide SCHEMBL28113733 0.77 ALDH1A1 (0.43) ALDH1A1SLC6A2TSHRMEN1KMT2A
SCHEMBL228320 0.77 ALDH1A1 (0.43) ALDH1A1SLC6A2TSHRMEN1KMT2A
Hydrochloric Acid SCHEMBL27825197 0.77 ALDH1A1 (0.43) ALDH1A1SLC6A2TSHRMEN1KMT2A
SCHEMBL9853603 0.77 ALDH1A1 (0.43) ALDH1A1SLC6A2TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0202498-B1 USE OF A THERMO-SETTING, POLYMERIZABLE COMPOSITION AND WIRING BOARD HITACHI, LTD. (JP) 1990-07-11 EP claimed
US-4738900-A HEAT RESISTANT DIELECTRIC LAYER OF A POLYMER OF AN AROMATIC DIMALEIMIDE AND AN AROMATIC DICYANAMIDE HITACHI, LTD. (JP) 1988-04-19 US claimed
EP-0202498-A2 Use of a thermo-setting, polymerizable composition and wiring board HITACHI, LTD. (JP) 1986-11-26 EP claimed
US-4546168-A POLYMERIZABLE EPOXY COMPOUNDS, PHENOLIC COMPOUNDS, AND TRIALLYL ISOCYANURATE COMPOUNDS HITACHI, LTD. (JP) 1985-10-08 US claimed
US-4486583-A MOLDING MATERIALS, COATINGS HITACHI, LTD. (JP) 1984-12-04 US claimed
US-4482703-A Thermosetting resin composition comprising dicyanamide and polyvalent imide HITACHI, LTD. (JP) 1984-11-13 US claimed
EP-0476589-B1 Multi-layer wiring substrate and production thereof HITACHI LTD (JP) 1996-06-12 EP disclosed
EP-0476589-A2 Multi-layer wiring substrate and production thereof HITACHI, LTD. (JP) 1992-03-25 EP disclosed
EP-0153603-B1 THERMOSETTING RESIN COMPOSITION, CURED PRODUCT, AND PRODUCTION OF CURED PRODUCT HITACHI, LTD. (JP) 1992-01-02 EP disclosed
EP-0102052-B1 HEAT-RESISTANT RESIN, THERMOSETTING COMPOSITION AFFORDING THE SAME AND PREPOLYMER THEREOF HITACHI, LTD. (JP) 1990-10-31 EP disclosed
EP-0202498-B1 USE OF A THERMO-SETTING, POLYMERIZABLE COMPOSITION AND WIRING BOARD HITACHI, LTD. (JP) 1990-07-11 EP disclosed
US-4738900-A HEAT RESISTANT DIELECTRIC LAYER OF A POLYMER OF AN AROMATIC DIMALEIMIDE AND AN AROMATIC DICYANAMIDE HITACHI, LTD. (JP) 1988-04-19 US disclosed
EP-0202498-A2 Use of a thermo-setting, polymerizable composition and wiring board HITACHI, LTD. (JP) 1986-11-26 EP disclosed
EP-0078039-B1 THERMOSETTING RESIN COMPOSITION, PREPOLYMER THEREOF AND CURED ARTICLE THEREOF Hitachi, Ltd. (JP) 1986-01-22 EP disclosed
US-4546168-A POLYMERIZABLE EPOXY COMPOUNDS, PHENOLIC COMPOUNDS, AND TRIALLYL ISOCYANURATE COMPOUNDS HITACHI, LTD. (JP) 1985-10-08 US disclosed
EP-0153603-A2 Thermosetting resin composition, cured product, and production of cured product HITACHI, LTD. (JP) 1985-09-04 EP disclosed
US-4486583-A MOLDING MATERIALS, COATINGS HITACHI, LTD. (JP) 1984-12-04 US disclosed
US-4482703-A Thermosetting resin composition comprising dicyanamide and polyvalent imide HITACHI, LTD. (JP) 1984-11-13 US disclosed
EP-0102052-A2 Heat-resistant resin, thermosetting composition affording the same and prepolymer thereof HITACHI, LTD. (JP) 1984-03-07 EP disclosed
EP-0078039-A1 Thermosetting resin composition, prepolymer thereof and cured article thereof Hitachi, Ltd. (JP) 1983-05-04 EP disclosed