Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985163 | 1.00 | CA1 (0.53) | CA1CA2NFKB1CA4KDM4E | |
| SCHEMBL819054 | 0.86 | CA1 (0.56) | CA1CA2NFKB1CA4KDM4E | |
| SCHEMBL28414685 | 0.86 | CA1 (0.56) | CA1CA2NFKB1CA4KDM4E | |
| SCHEMBL8575018 | 0.84 | CA1 (0.55) | CA1CA2NFKB1CA4KDM4E | |
| SCHEMBL8099512 | 0.83 | CA1 (0.53) | CA1CA2NFKB1CA4KDM4E | |
| SCHEMBL1072584 | 0.83 | CA1 (0.53) | CA1CA2NFKB1CA4KDM4E | |
| SCHEMBL8099514 | 0.83 | CA1 (0.53) | CA1CA2NFKB1CA4KDM4E | |
| SCHEMBL584958 | 0.81 | CA1 (0.51) | CA1CA2NFKB1CA4KDM4E | |
| SCHEMBL9354503 | 0.80 | CA1 (0.50) | CA1CA2NFKB1CA4KDM4E | |
| SCHEMBL6851902 | 0.78 | CA1 (0.47) | CA1CA2NFKB1CA4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541286-A | Bradykinin antagonist pseudopeptide derivatives of olefinic aminoalkanoic acids | SCIOS NOVA INC. (US) | 1996-07-30 | — | — | US | disclosed |
| US-5444048-A | Antiinflammatory agents, analgesics | SCIOS NOVA, INC. (US) | 1995-08-22 | — | — | US | disclosed |