SCHEMBL819054

SCHEMBL819054

CC(C)c1ccccc1/C=C/C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
NFKB1 P19838 1/20 0.56
CA4 P22748 1/20 0.56
KDM4E B2RXH2 4/20 0.54
MAPT P10636 2/20 0.49
HTT P42858 1/20 0.49
MAPK1 P28482 1/20 0.49
HDAC3 O15379 1/20 0.48
TNKS O95271 1/20 0.48
HDAC4 P56524 1/20 0.48
HDAC1 Q13547 1/20 0.48
HCAR2 Q8TDS4 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC10 Q969S8 1/20 0.48
HDAC11 Q96DB2 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
TNKS2 Q9H2K2 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28414685 1.00 CA1 (0.56) CA1CA2NFKB1CA4KDM4E
SCHEMBL8575018 0.87 CA1 (0.55) CA1CA2NFKB1CA4KDM4E
SCHEMBL8985156 0.86 CA1 (0.53) CA1CA2NFKB1CA4KDM4E
SCHEMBL8985163 0.86 CA1 (0.53) CA1CA2NFKB1CA4KDM4E
SCHEMBL1072584 0.86 CA1 (0.53) CA1CA2NFKB1CA4KDM4E
SCHEMBL8099512 0.86 CA1 (0.53) CA1CA2NFKB1CA4KDM4E
SCHEMBL8099514 0.86 CA1 (0.53) CA1CA2NFKB1CA4KDM4E
SCHEMBL584958 0.84 CA1 (0.51) CA1CA2NFKB1CA4KDM4E
SCHEMBL1173259 0.84 KDM4E (0.66) CA1CA2NFKB1CA4KDM4E
SCHEMBL10697312 0.84 PTPN1 (0.46) CA1CA2NFKB1CA4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3443056-B1 ODOURLESS SHEA BASED ESTERS AAK AB PUBL (SE) 2022-08-10 EP claimed
EP-2967038-B1 METHODS, COMPOUNDS AND COMPOSITIONS FOR REPELLING INSECTS AND ARACHNIDS NATIONAL CENTER FOR SCIENT RESEARCH DEMOKRITOS (GR) 2019-05-08 EP claimed
US-20160029643-A1 Methods, Compounds and Compositions for Repelling Insects and/or Arachnids NATIONAL CENTER FOR SCIENTIFIC RESEARCH "DEMOKRITOS" (GB) 2016-02-04 US claimed
EP-2967038-A2 METHODS, COMPOUNDS AND COMPOSITIONS FOR REPELLING INSECTS AND ARACHNIDS NATIONAL CENTER FOR SCIENTIFIC RESEARCH "DEMOKRITOS" (GR) 2016-01-20 EP claimed
WO-2014140314-A2 METHODS, COMPOUNDS AND COMPOSITIONS FOR REPELLING INSECTS AND/OR ARACHNIDS UNIVERSITE DE NEUCHATEL (CH) 2014-09-18 WO claimed
EP-1716159-B1 BICYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS MOMENTIVE PERFORMANCE MAT INC (US) 2011-07-13 EP claimed
EP-1967080-B1 Non-aldehyde cinnamon flavor and delivery systems therefor CADBURY ADAMS USA LLC (US) 2010-06-02 EP claimed
EP-1697386-B1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES GEN ELECTRIC (US) 2007-10-10 EP claimed
US-20070093558-A1 Electrostatic aerosol compositions RECKITT BENCKISER (UK) LIMITED, A UK CORPORATION 2007-04-26 US claimed
EP-1409605-A2 ELECTROSTATIC AEROSOL COMPOSITIONS Reckitt Benckiser (U.K.) LIMITED (GB) 2004-04-21 EP claimed
US-20030096878-A1 Electrostatic aerosol compositions RECKITT BENCKISER (UK) LIMITED 2003-05-22 US claimed
WO-2001018145-A2 ELECTROSTATIC AEROSOL COMPOSITIONS RECKITT BENCKISER (UK) LIMITED (GB) 2001-03-15 WO claimed
EP-0428276-B1 Acaricidal composition TAKASAGO PERFUMERY CO LTD (JP) 1998-09-16 EP claimed
US-20230382865-A1 HISTONE DEMETHYLASE 5 INHIBITORS AND USES THEREOF DANA-FARBER CANCER INSTITUTE, INC. (US) 2023-11-30 US disclosed
EP-2145042-B2 TEXTILE SCENTING HENKEL AG & CO KGAA (DE) 2021-10-06 EP disclosed
EP-3590940-B1 HEXAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AND RELATED COMPOUNDS AS AUTOTAXIN (ATX) INHIBITORS AND AS INHIBITORS OF THE LYSOPHOSPHATIDIC ACID (LPA) PRODUCTION FOR TREATING E.G. RENAL DISEASES HOFFMANN LA ROCHE (CH) 2021-06-09 EP disclosed
EP-1123950-A1 Method for preventing settlement of aquatic fouling organisms Nippon Paint Co., Ltd. (JP) 2001-08-16 EP disclosed
WO-2001018145-A2 ELECTROSTATIC AEROSOL COMPOSITIONS RECKITT BENCKISER (UK) LIMITED (GB) 2001-03-15 WO disclosed
EP-0702065-A2 Method for preventing settlement of aquatic fouling organisms Nippon Paint Co., Ltd. (JP) 1996-03-20 EP disclosed
US-4748161-A Triterpenyl esters of organic acids and hypolipidemic agents composed of them AMANO PHARMACEUTICAL CO., LTD. (JP) 1988-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230382865-A1 HISTONE DEMETHYLASE 5 INHIBITORS AND USES THEREOF KDM5A, KDM5B, KDM5C CA1 239/4885CA2 698/4885NFKB1 1174/4885
US-20160029643-A1 Methods, Compounds and Compositions for Repelling Insects and/or Arachnids ACHE, NISCH, BCHE CA1 728/4885CA2 1297/4885NFKB1 4747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.