Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NEK2 | P51955 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29119706 | 0.69 | KDM4E (0.48) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL30915761 | 0.68 | KDM4E (0.46) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL30915762 | 0.68 | KDM4E (0.39) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL9342154 | 0.68 | KDM4E (0.46) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| Hydrochloric Acid SCHEMBL8985222 | 0.67 | KDM4E (0.45) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL29119707 | 0.67 | KDM4E (0.45) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL28608994 | 0.66 | KDM4E (0.37) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL31132517 | 0.66 | MMP3 (0.41) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| Hydrochloric Acid SCHEMBL7324922 | 0.65 | MMP3 (0.40) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| Hydrochloric Acid SCHEMBL7333482 | 0.65 | MMP3 (0.38) | KDM4EHSD17B10USP2HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547961-A | USING TETRAHYDROIMIDAZOPYRIDINE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| US-5336679-A | Treatment of irritable bowel syndrome | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1994-08-09 | — | — | US | disclosed |
| EP-0532754-A1 | TETRAHYDROIMIDAZOPYRIDINE DERIVATIVE OR ITS SALT | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-24 | — | — | EP | disclosed |