Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 8/20 | 0.53 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.37 |
| ▸ | NEK2 | P51955 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31132960 | 0.98 | ADRA1A (0.51) | ADRA1ANAMPTADRA1DADRA1BKDM4E | |
| SCHEMBL16112524 | 0.85 | ADRA1A (0.48) | ADRA1ANAMPTADRA1DADRA1BKDM4E | |
| SCHEMBL30630523 | 0.79 | ADRA1A (0.52) | ADRA1ANAMPTADRA1DADRA1BADRA2A | |
| SCHEMBL16067955 | 0.78 | POLB (0.46) | ADRA1AKDM4ECYP2C19 | |
| SCHEMBL24424305 | 0.76 | ADRA1A (0.49) | ADRA1ANAMPTADRA1DADRA1BKDM4E | |
| SCHEMBL9342154 | 0.73 | KDM4E (0.46) | ADRA1AADRA1DADRA1BKDM4ECYP2C19 | |
| SCHEMBL30915761 | 0.73 | KDM4E (0.46) | ADRA1AADRA1DADRA1BKDM4ECYP2C19 | |
| SCHEMBL31133117 | 0.73 | NOTUM (0.37) | KDM4ECYP2C19NOTUMNEK2GABRP | |
| SCHEMBL17338866 | 0.73 | PDPK1 (0.41) | KDM4ECYP2C19NOTUMCDK9GABRP | |
| SCHEMBL23641525 | 0.73 | ADRA1A (0.40) | ADRA1ANAMPTADRA1DADRA1BCDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929697-A | Azabenzimidazole compounds and medicaments | 日本新药株式会社 | 2022-08-19 | — | — | CN | claimed |
| CN-114929697-A | Azabenzimidazole compounds and medicaments | 日本新药株式会社 | 2022-08-19 | — | — | CN | disclosed |
| US-5547961-A | USING TETRAHYDROIMIDAZOPYRIDINE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| US-5336679-A | Treatment of irritable bowel syndrome | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1994-08-09 | — | — | US | disclosed |
| EP-0532754-A1 | TETRAHYDROIMIDAZOPYRIDINE DERIVATIVE OR ITS SALT | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-24 | — | — | EP | disclosed |