Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.52 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985510 | 0.87 | MAPK14 (0.67) | MAPK14KDM4EHPGDHSD17B10PTGS1 | |
| SCHEMBL8985288 | 0.87 | MAPK14 (0.67) | MAPK14KDM4EHPGDHSD17B10PTGS1 | |
| SCHEMBL8985360 | 0.87 | MAPK14 (0.40) | MAPK14TTRKDM4EMEN1USP2 | |
| SCHEMBL8985251 | 0.86 | MAPK14 (0.47) | MAPK14KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL8985412 | 0.84 | MAPK14 (0.59) | MAPK14KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL8985541 | 0.83 | MAPK14 (0.56) | MAPK14KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL8985537 | 0.82 | MAPK14 (0.51) | MAPK14PTGS1PTGS2NOTUMTDP1 | |
| SCHEMBL8985259 | 0.77 | MAPK14 (0.50) | MAPK14KDM4EALDH1A1LMNAPTGS1 | |
| SCHEMBL7623155 | 0.77 | PTGS1 (0.67) | MAPK14KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL8985263 | 0.76 | NOTUM (0.41) | MAPK14ALDH1A1PTGS1PTGS2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |