Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985323 | 1.00 | MAPK14 (0.52) | MAPK14PTGS1PTGS2HPGDNPC1 | |
| SCHEMBL8985239 | 0.94 | NPC1 (0.50) | MAPK14PTGS1PTGS2HPGDNPC1 | |
| SCHEMBL8985467 | 0.91 | MAPK14 (0.60) | MAPK14PTGS1PTGS2HPGDNPC1 | |
| SCHEMBL8985360 | 0.88 | MAPK14 (0.40) | MAPK14PTGS1PTGS2HPGDNPC1 | |
| SCHEMBL8985416 | 0.88 | NPC1 (0.40) | MAPK14PTGS1PTGS2HPGDNPC1 | |
| SCHEMBL8985209 | 0.88 | SMN1; SMN2 (0.45) | MAPK14PTGS1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL8985559 | 0.87 | MAPK14 (0.49) | MAPK14PTGS1PTGS2HPGDNPC1 | |
| SCHEMBL8985225 | 0.86 | MAPK14 (0.55) | MAPK14PTGS1PTGS2HPGDNPC1 | |
| SCHEMBL8985288 | 0.86 | MAPK14 (0.67) | MAPK14PTGS1PTGS2HPGDOPRD1 | |
| SCHEMBL8985510 | 0.86 | MAPK14 (0.67) | MAPK14PTGS1PTGS2HPGDOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |