SCHEMBL8986136

SCHEMBL8986136

[NH]c1ccc2cc(Br)ccc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.56
MAPT P10636 2/20 0.52
KDM4E B2RXH2 1/20 0.52
MEN1 O00255 1/20 0.52
ALDH1A1 P00352 1/20 0.52
KMT2A Q03164 1/20 0.52
BACE1 P56817 2/20 0.40
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
AHR P35869 2/20 0.38
NR4A2 P43354 1/20 0.38
NCEH1 Q6PIU2 1/20 0.37
NOS1 P29475 2/20 0.35
METAP2 P50579 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
HTT P42858 1/20 0.35
CSNK2A1 P68400 1/20 0.35
DYRK1A Q13627 1/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11803852 0.83 CYP2A6 (0.37) CYP2A6ALDH1A1CYP1A2TDP1
SCHEMBL192166 0.83 CYP2A6 (0.77) CYP2A6MAPTKDM4EMEN1ALDH1A1
SCHEMBL29353067 0.83 CYP2A6 (0.77) CYP2A6MAPTKDM4EMEN1ALDH1A1
SCHEMBL4648267 0.77 ALDH1A1 (0.38) CYP2A6ALDH1A1CYP1A2ALOX15TDP1
SCHEMBL17849089 0.77 CYP2A6 (0.68) CYP2A6MAPTKDM4EMEN1ALDH1A1
SCHEMBL23312077 0.77 CYP2A6 (0.68) CYP2A6MAPTKDM4EMEN1ALDH1A1
SCHEMBL13153611 0.77 CYP2A6 (0.68) CYP2A6MAPTKDM4EMEN1ALDH1A1
SCHEMBL148642 0.77 CYP2A6 (0.68) CYP2A6MAPTKDM4EMEN1ALDH1A1
SCHEMBL17849092 0.77 CYP2A6 (0.68) CYP2A6MAPTKDM4EMEN1ALDH1A1
SCHEMBL29427549 0.77 CYP2A6 (0.68) CYP2A6MAPTKDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0476107-B1 PROCESS FOR IDENTIFYING CANDIDA ALBICANS BY MEANS OF CHROMOGENIC SUBSTANCES STAGO DIAGNOSTICA (FR) 1996-06-19 EP disclosed
US-5449612-A Process for identifying candida by means of chromogenic substances SERBIO (FR) 1995-09-12 US disclosed
WO-1991014787-A1 PROCESS FOR IDENTIFYING CANDIDA BY MEANS OF CHROMOGENIC SUBSTANCES SERBIO (FR) 1991-10-03 WO disclosed