Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.46 |
| ▸ | MEN1 | O00255 | 10/20 | 0.46 |
| ▸ | POLB | P06746 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933459 | 1.00 | KMT2A (0.46) | KMT2AMEN1POLBGAAMAPT | |
| SCHEMBL8991958 | 1.00 | KMT2A (0.46) | KMT2AMEN1POLBGAAMAPT | |
| SCHEMBL8310599 | 0.89 | MAPT (0.56) | KMT2AMEN1POLBGAAMAPT | |
| SCHEMBL8310604 | 0.89 | MAPT (0.56) | KMT2AMEN1POLBGAAMAPT | |
| SCHEMBL8309496 | 0.85 | FABP4 (0.55) | KMT2AMEN1POLBGAAMAPT | |
| SCHEMBL8537293 | 0.82 | GAA (0.38) | KMT2AMEN1POLBGAAMAPT | |
| SCHEMBL8535804 | 0.82 | GAA (0.38) | KMT2AMEN1POLBGAAMAPT | |
| SCHEMBL8537292 | 0.82 | GAA (0.38) | KMT2AMEN1POLBGAAMAPT | |
| SCHEMBL8307815 | 0.81 | DYRK1A (0.61) | KMT2AMEN1POLBGAAMAPT | |
| SCHEMBL8307819 | 0.81 | DYRK1A (0.61) | KMT2AMEN1POLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523314-A | RHODANINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1996-06-04 | — | — | US | disclosed |