Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLB1 | P16278 | 1/20 | 0.36 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 3/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 4/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8986324 | 1.00 | GLB1 (0.36) | GLB1GBA2GBA1SLC5A2SLC5A1 | |
| SCHEMBL20723768 | 0.74 | SLC5A2 (0.40) | SLC5A2SLC5A1 | |
| SCHEMBL20723767 | 0.74 | SLC5A2 (0.40) | SLC5A2SLC5A1 | |
| SCHEMBL18316490 | 0.74 | SLC5A2 (0.40) | SLC5A2SLC5A1 | |
| SCHEMBL4279547 | 0.74 | SLC5A2 (0.40) | SLC5A2SLC5A1 | |
| SCHEMBL18393117 | 0.72 | PYGB (0.31) | — | |
| SCHEMBL3963397 | 0.71 | SLC5A2 (0.38) | SLC5A2SLC5A1GAA | |
| SCHEMBL12137310 | 0.71 | GRIN2B (0.46) | FUCA1LMNA | |
| SCHEMBL8199991 | 0.70 | SLC5A2 (0.40) | SLC5A2SLC5A1 | |
| SCHEMBL3956073 | 0.70 | SLC5A2 (0.40) | SLC5A2SLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565434-A | REDUCING INTRAOCULAR PRESSURE WITH TOPICAL APPLICATION | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1996-10-15 | — | — | US | disclosed |