Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 10/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302920 | 1.00 | GRM2 (0.47) | GRM2SIGMAR1F10MAOA | |
| SCHEMBL5617993 | 1.00 | GRM2 (0.47) | GRM2SIGMAR1F10MAOA | |
| SCHEMBL5617991 | 1.00 | GRM2 (0.47) | GRM2SIGMAR1F10MAOA | |
| SCHEMBL7302909 | 1.00 | GRM2 (0.47) | GRM2SIGMAR1F10MAOA | |
| SCHEMBL7299934 | 0.94 | GRM2 (0.52) | GRM2SIGMAR1F10MAOA | |
| SCHEMBL7299930 | 0.94 | GRM2 (0.52) | GRM2SIGMAR1F10MAOA | |
| SCHEMBL5634033 | 0.88 | SIGMAR1 (0.48) | GRM2SIGMAR1F10 | |
| SCHEMBL7309920 | 0.88 | GRM2 (0.47) | GRM2SIGMAR1F10 | |
| SCHEMBL5634028 | 0.88 | SIGMAR1 (0.48) | GRM2SIGMAR1F10 | |
| SCHEMBL5617533 | 0.88 | SIGMAR1 (0.48) | GRM2SIGMAR1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574055-A | COGNITIVE AND NEURODEGENERATIVE DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1996-11-12 | — | — | US | disclosed |