SCHEMBL8986469

SCHEMBL8986469

CCc1c(C)c2cc3nc(cc4ccc(cc5nc(cc1[nH]2)C=C5)[nH]4)C=C3.[Al]

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.32
▸ STAT1 P42224 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27568822 0.84 STAT3 (0.38) STAT3STAT1
SCHEMBL10433085 0.82 STAT3 (0.32) STAT3STAT1
SCHEMBL8858186 0.80 STAT3 (0.37) STAT3STAT1
SCHEMBL3720964 0.80 KCNH2 (0.34) —
SCHEMBL28306335 0.79 STAT3 (0.31) STAT3STAT1
Methoxymethane SCHEMBL27941356 0.79 STAT3 (0.36) STAT3STAT1
SCHEMBL4944697 0.79 KCNH2 (0.34) —
SCHEMBL28320487 0.78 STAT3 (0.30) STAT3STAT1
SCHEMBL29710699 0.76 STAT3 (0.41) STAT3STAT1
SCHEMBL144247 0.76 STAT3 (0.47) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0510602-B1 Living polymerization method KANSAI PAINT CO LTD (JP) 1996-06-26 — — EP disclosed
US-5328970-A Porphyrin complex as catalyst with organo aluminum compounds for polymerization KANSAI PAINT CO., LTD. (JP) 1994-07-12 — — US disclosed
EP-0510602-A1 Living polymerization method KANSAI PAINT CO., LTD. (JP) 1992-10-28 — — EP disclosed
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