Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8758334 | 1.00 | KDM4E (0.45) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8986564 | 0.80 | MAPT (0.53) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8758281 | 0.80 | MAPT (0.53) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8416379 | 0.78 | KMT2A (0.64) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL8416381 | 0.78 | KMT2A (0.64) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL27683596 | 0.77 | MAPT (0.48) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1786483 | 0.76 | KDM4E (0.52) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL797091 | 0.74 | MAPT (0.50) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL797092 | 0.74 | MAPT (0.50) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL807793 | 0.74 | MAPT (0.50) | MEN1KMT2AMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480983-A | ANALGESICS, HYPOTENSIVE AGENTS | LABORATOIRES UPSA (FR) | 1996-01-02 | — | — | US | disclosed |