Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.70 |
| ▸ | MAPT | P10636 | 10/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.70 |
| ▸ | HTT | P42858 | 6/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 5/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | PKM | P14618 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8757527 | 1.00 | ALDH1A1 (0.70) | ALDH1A1MAPTNPSR1HTTSMN1; SMN2 | |
| SCHEMBL8986557 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPTNPSR1HTTSMN1; SMN2 | |
| SCHEMBL8758840 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPTNPSR1HTTSMN1; SMN2 | |
| SCHEMBL6802019 | 0.81 | ALDH1A1 (0.70) | ALDH1A1MAPTNPSR1HTTSMN1; SMN2 | |
| SCHEMBL8986584 | 0.80 | ALDH1A1 (0.74) | ALDH1A1MAPTNPSR1HTTSMN1; SMN2 | |
| SCHEMBL8758713 | 0.80 | ALDH1A1 (0.74) | ALDH1A1MAPTNPSR1HTTSMN1; SMN2 | |
| SCHEMBL8758340 | 0.80 | ALDH1A1 (1.00) | ALDH1A1MAPTNPSR1HTTSMN1; SMN2 | |
| SCHEMBL8986604 | 0.80 | ALDH1A1 (1.00) | ALDH1A1MAPTNPSR1HTTSMN1; SMN2 | |
| SCHEMBL9500175 | 0.79 | ALDH1A1 (0.73) | ALDH1A1MAPTNPSR1HTTSMN1; SMN2 | |
| SCHEMBL8758882 | 0.79 | ALDH1A1 (0.73) | ALDH1A1MAPTNPSR1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480983-A | ANALGESICS, HYPOTENSIVE AGENTS | LABORATOIRES UPSA (FR) | 1996-01-02 | — | — | US | disclosed |
| US-5229505-A | CNS and cardiovascular effects | LABORATOIRES UPSA (FR) | 1993-07-20 | — | — | US | disclosed |