Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424432 | 1.00 | POLB (0.51) | POLBCYP2C19ALDH1A1TSHRMEN1 | |
| SCHEMBL8986747 | 1.00 | POLB (0.51) | POLBCYP2C19ALDH1A1TSHRMEN1 | |
| SCHEMBL15226929 | 1.00 | POLB (0.51) | POLBCYP2C19ALDH1A1TSHRMEN1 | |
| SCHEMBL7424434 | 1.00 | POLB (0.51) | POLBCYP2C19ALDH1A1TSHRMEN1 | |
| SCHEMBL4658040 | 0.86 | POLB (0.53) | POLBCYP2C19ALDH1A1TSHRMEN1 | |
| SCHEMBL10926755 | 0.85 | POLB (0.50) | POLBCYP2C19ALDH1A1TSHRMEN1 | |
| SCHEMBL3096665 | 0.85 | ALDH1A1 (0.55) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL2827224 | 0.84 | MEN1 (0.51) | POLBCYP2C19ALDH1A1TSHRMEN1 | |
| SCHEMBL258742 | 0.82 | ALDH1A1 (0.51) | POLBCYP2C19ALDH1A1TSHRMEN1 | |
| SCHEMBL258592 | 0.82 | ALDH1A1 (0.51) | POLBCYP2C19ALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008603-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | SEATTLE GENETICS, INC. (US) | 2007-01-18 | — | — | WO | disclosed |
| US-5552410-A | 1,2,3,4,-tetrahydroquinoline-8-sulphonic acid chlorides and acids, their preparation and their use as synthetic intermediates | SYNTHELABO (FR) | 1996-09-03 | — | — | US | disclosed |
| US-5476942-A | 1-[2-amino-5-[1-(triphenylmethyl)-1H-imidazol-4-YL]-1-oxopentyl] piperidine derivatives, their preparation and their use as synthetic intermediates | SYNTHELABO (FR) | 1995-12-19 | — | — | US | disclosed |
| EP-0643047-A1 | 1(2-amino-5-(1-(triphenylmethyl)-1H-imidazol-4-yl)-1-oxopentyl)piperidine derivatives, their preparation and their use as synthetic intermediates | SYNTHELABO (FR) | 1995-03-15 | — | — | EP | disclosed |
| EP-0643046-A1 | 1,2,3,4-Tetrahydrochinolin-8-sulfonic acid and its chlorides as intermediates | SYNTHELABO (FR) | 1995-03-15 | — | — | EP | disclosed |