Toluene

Toluene

SCHEMBL8986744

C=CC=CCCCCCC.Cc1ccccc1

nearest known ligand 0.42

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Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SOAT2 O75908 1/20 0.42
SOAT1 P35610 1/20 0.42
FASN P49327 1/20 0.41
FAAH O00519 5/20 0.40
EPHX2 P34913 3/20 0.40
TSHR P16473 2/20 0.39
CES1 P23141 1/20 0.39
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39
ALDH1A1 P00352 1/20 0.38
CYP2D6 P10635 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL517662 0.84 SOAT2 (0.40) SOAT2SOAT1FASNFAAHEPHX2
Styrene SCHEMBL15649632 0.83 TSHR (0.47) SOAT2SOAT1FASNFAAHEPHX2
Toluene SCHEMBL11011055 0.82 TSHR (0.61) SOAT2SOAT1FAAHEPHX2TSHR
Toluene SCHEMBL11023406 0.82 TSHR (0.61) SOAT2SOAT1FAAHEPHX2TSHR
Toluene SCHEMBL782975 0.82 TSHR (0.61) SOAT2SOAT1FAAHEPHX2TSHR
Heptane SCHEMBL6130166 0.82 TSHR (0.61) SOAT2SOAT1FAAHEPHX2TSHR
Toluene SCHEMBL8147547 0.82 TSHR (0.61) SOAT2SOAT1FAAHEPHX2TSHR
SCHEMBL217258 0.82 TSHR (0.56) FASNFAAHTSHRALDH1A1
SCHEMBL22468755 0.82 TSHR (0.56) FASNFAAHTSHRALDH1A1
SCHEMBL22468753 0.82 TSHR (0.56) FASNFAAHTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717754-A1 CATALYST COMPOSITIONS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1996-06-26 EP disclosed
WO-1995004087-A1 CATALYST COMPOSITIONS SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1995-02-09 WO disclosed