Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8986766 | 1.00 | BRD4 (0.34) | BRD4CREBBPF2 | |
| SCHEMBL8986760 | 1.00 | BRD4 (0.34) | BRD4CREBBPF2 | |
| SCHEMBL21692939 | 0.78 | HTR2C (0.41) | BRD4CREBBP | |
| SCHEMBL7797306 | 0.76 | MEN1 (0.36) | BRD4CREBBPF2 | |
| SCHEMBL13075669 | 0.76 | MAOA (0.40) | BRD4CREBBP | |
| SCHEMBL28494482 | 0.72 | BRD4 (0.36) | BRD4CREBBPF2 | |
| SCHEMBL7419402 | 0.70 | F2 (0.41) | F2 | |
| SCHEMBL7419399 | 0.70 | F2 (0.41) | F2 | |
| SCHEMBL30788469 | 0.70 | F2 (0.44) | F2 | |
| SCHEMBL7423427 | 0.70 | F2 (0.44) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552410-A | 1,2,3,4,-tetrahydroquinoline-8-sulphonic acid chlorides and acids, their preparation and their use as synthetic intermediates | SYNTHELABO (FR) | 1996-09-03 | — | — | US | disclosed |
| US-5476942-A | 1-[2-amino-5-[1-(triphenylmethyl)-1H-imidazol-4-YL]-1-oxopentyl] piperidine derivatives, their preparation and their use as synthetic intermediates | SYNTHELABO (FR) | 1995-12-19 | — | — | US | disclosed |
| EP-0643047-A1 | 1(2-amino-5-(1-(triphenylmethyl)-1H-imidazol-4-yl)-1-oxopentyl)piperidine derivatives, their preparation and their use as synthetic intermediates | SYNTHELABO (FR) | 1995-03-15 | — | — | EP | disclosed |
| EP-0643046-A1 | 1,2,3,4-Tetrahydrochinolin-8-sulfonic acid and its chlorides as intermediates | SYNTHELABO (FR) | 1995-03-15 | — | — | EP | disclosed |