Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 18/20 | 0.75 |
| ▸ | TOP2A | P11388 | 1/20 | 0.51 |
| ▸ | PDE5A | O76074 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9291792 | 1.00 | LTB4R (0.75) | LTB4RTOP2APDE5A | |
| SCHEMBL8987489 | 1.00 | LTB4R (0.75) | LTB4RTOP2APDE5A | |
| SCHEMBL11184442 | 0.95 | LTB4R (0.67) | LTB4RTOP2APDE5A | |
| SCHEMBL8987362 | 0.88 | LTB4R (0.58) | LTB4RTOP2APDE5A | |
| SCHEMBL8987185 | 0.86 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8987194 | 0.86 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8987184 | 0.86 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8987249 | 0.86 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8986991 | 0.83 | LTB4R (0.80) | LTB4R | |
| SCHEMBL8987406 | 0.81 | LTB4R (0.63) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492915-A | ANTIINFLAMMATORY AGENTS | RHONE-POULENC RORER S.A. (FR) | 1996-02-20 | — | — | US | disclosed |
| US-5366982-A | Antiinflammatory agents or antihistamines | RHONE-POULENC RORER S.A. (FR) | 1994-11-22 | — | — | US | disclosed |