Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 16/20 | 0.83 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9291839 | 0.91 | LTB4R (1.00) | LTB4RSLC6A9 | |
| SCHEMBL8987034 | 0.89 | LTB4R (0.83) | LTB4R | |
| SCHEMBL8987128 | 0.86 | LTB4R (0.82) | LTB4R | |
| SCHEMBL8987047 | 0.80 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8987009 | 0.77 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8987340 | 0.77 | LTB4R (0.81) | LTB4R | |
| SCHEMBL8987342 | 0.76 | LTB4R (0.82) | LTB4R | |
| SCHEMBL8987321 | 0.76 | LTB4R (0.82) | LTB4R | |
| SCHEMBL8987150 | 0.76 | LTB4R (0.79) | LTB4R | |
| SCHEMBL8987001 | 0.75 | LTB4R (0.79) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492915-A | ANTIINFLAMMATORY AGENTS | RHONE-POULENC RORER S.A. (FR) | 1996-02-20 | — | — | US | disclosed |
| US-5366982-A | Antiinflammatory agents or antihistamines | RHONE-POULENC RORER S.A. (FR) | 1994-11-22 | — | — | US | disclosed |