SCHEMBL8986972

SCHEMBL8986972

O=C(O)CCCCCOc1cc(-c2ccccc2)cc(-c2ccc(Cl)cc2)n1

nearest known ligand 0.86

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 20/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8987157 1.00 LTB4R (0.86) LTB4R
SCHEMBL8987280 0.96 LTB4R (0.79) LTB4R
SCHEMBL8987440 0.93 LTB4R (1.00) LTB4R
SCHEMBL6757530 0.93 LTB4R (1.00) LTB4R
SCHEMBL8987039 0.92 LTB4R (1.00) LTB4R
SCHEMBL8987431 0.90 LTB4R (0.80) LTB4R
SCHEMBL8987354 0.89 LTB4R (0.87) LTB4R
SCHEMBL8987444 0.89 LTB4R (0.84) LTB4R
SCHEMBL8987048 0.89 LTB4R (0.84) LTB4R
SCHEMBL8987353 0.89 LTB4R (0.78) LTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5492915-A ANTIINFLAMMATORY AGENTS RHONE-POULENC RORER S.A. (FR) 1996-02-20 US disclosed
US-5366982-A Antiinflammatory agents or antihistamines RHONE-POULENC RORER S.A. (FR) 1994-11-22 US disclosed