Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | IDO1 | P14902 | 4/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10647998 | 0.84 | IDO1 (0.47) | PDGFRBKMT2AIDO1SIRT5KDM4E | |
| Hydrochloric Acid SCHEMBL10651452 | 0.83 | IDO1 (0.46) | PDGFRBKMT2AIDO1SIRT5KDM4E | |
| SCHEMBL10510719 | 0.81 | MEN1 (0.44) | PDGFRBKMT2AIDO1MEN1KDM4E | |
| SCHEMBL8987430 | 0.78 | KDM4E (0.41) | PDGFRBKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL8987328 | 0.78 | PARP1 (0.48) | KMT2AMEN1CCNE1CDK2KDM4E | |
| SCHEMBL15503669 | 0.74 | KMT2A (0.53) | KMT2AMEN1CCNE2CDK4CCND1 | |
| SCHEMBL4623876 | 0.73 | MEN1 (0.66) | KMT2AMEN1CCNE2CDK4CCND1 | |
| SCHEMBL7210265 | 0.72 | MAPK14 (0.50) | KDM4ETDP1ALDH1A1LMNAMAPT | |
| SCHEMBL21852751 | 0.70 | ALDH1A1 (0.67) | KMT2AMEN1KDM4ETDP1ALDH1A1 | |
| SCHEMBL16652457 | 0.70 | ALDH1A1 (0.68) | PDGFRBIDO1SIRT5KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492915-A | ANTIINFLAMMATORY AGENTS | RHONE-POULENC RORER S.A. (FR) | 1996-02-20 | — | — | US | disclosed |
| US-5366982-A | Antiinflammatory agents or antihistamines | RHONE-POULENC RORER S.A. (FR) | 1994-11-22 | — | — | US | disclosed |