SCHEMBL8987014

SCHEMBL8987014

COC(=O)C(C)(C)CCCCOc1cc(-c2ccccc2)c2cc(Cl)ccc2n1

nearest known ligand 0.83

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 20/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8987480 0.93 LTB4R (0.84) LTB4R
SCHEMBL8987403 0.91 LTB4R (1.00) LTB4R
SCHEMBL8987213 0.90 LTB4R (0.83) LTB4R
SCHEMBL8986979 0.89 LTB4R (0.67) LTB4R
SCHEMBL8987177 0.89 LTB4R (0.82) LTB4R
SCHEMBL8987156 0.89 LTB4R (0.84) LTB4R
SCHEMBL8987003 0.84 LTB4R (0.69) LTB4R
SCHEMBL8987277 0.84 LTB4R (1.00) LTB4R
SCHEMBL8987393 0.83 LTB4R (0.83) LTB4R
SCHEMBL8987029 0.83 LTB4R (0.68) LTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5492915-A ANTIINFLAMMATORY AGENTS RHONE-POULENC RORER S.A. (FR) 1996-02-20 US disclosed
US-5366982-A Antiinflammatory agents or antihistamines RHONE-POULENC RORER S.A. (FR) 1994-11-22 US disclosed