SCHEMBL8987350

SCHEMBL8987350

COc1ccc(-c2cc(OCCCCC(C)(C)C(=O)O)nc(-c3ccccc3)c2)cc1

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6760742 0.92 LTB4R (1.00) LTB4R
SCHEMBL8987145 0.92 LTB4R (0.72) LTB4R
SCHEMBL8987108 0.91 LTB4R (1.00) LTB4R
SCHEMBL8987035 0.91 LTB4R (1.00) LTB4R
SCHEMBL8987360 0.91 LTB4R (0.80) LTB4R
SCHEMBL8987390 0.88 LTB4R (1.00) LTB4R
SCHEMBL8987410 0.88 LTB4R (0.87) LTB4R
SCHEMBL8987224 0.88 LTB4R (0.87) LTB4R
SCHEMBL8987139 0.87 LTB4R (0.84) LTB4R
SCHEMBL8986942 0.85 LTB4R (0.80) LTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5492915-A ANTIINFLAMMATORY AGENTS RHONE-POULENC RORER S.A. (FR) 1996-02-20 US disclosed
US-5366982-A Antiinflammatory agents or antihistamines RHONE-POULENC RORER S.A. (FR) 1994-11-22 US disclosed