SCHEMBL8987484

SCHEMBL8987484

CC(C)(CCCCOc1cccc(-c2ccccc2)n1)C(=O)O

nearest known ligand 0.74

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 19/20 0.74
PPARA Q07869 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8987028 0.89 LTB4R (0.60) LTB4R
SCHEMBL6760742 0.85 LTB4R (1.00) LTB4R
SCHEMBL8987108 0.84 LTB4R (1.00) LTB4R
SCHEMBL8987035 0.84 LTB4R (1.00) LTB4R
SCHEMBL6757555 0.82 LTB4R (0.78) LTB4R
SCHEMBL12747713 0.82 LTB4R (0.56) LTB4RPPARA
SCHEMBL8987471 0.81 LTB4R (0.82) LTB4R
SCHEMBL9292185 0.81 LTB4R (0.72) LTB4RPPARA
SCHEMBL12747734 0.81 LTB4R (0.57) LTB4RPPARA
SCHEMBL8987360 0.80 LTB4R (0.80) LTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5492915-A ANTIINFLAMMATORY AGENTS RHONE-POULENC RORER S.A. (FR) 1996-02-20 US disclosed
US-5366982-A Antiinflammatory agents or antihistamines RHONE-POULENC RORER S.A. (FR) 1994-11-22 US disclosed