SCHEMBL8987626

SCHEMBL8987626

CC(C)(C)CC(C)(C)c1ccc2c(c1)Sc1cc(C(C)(C)CC(C)(C)C)ccc1OP(=O)(O)O2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.39
CYP3A4 P08684 3/20 0.38
CYP2D6 P10635 1/20 0.38
HIF1A Q16665 1/20 0.38
GPR84 Q9NQS5 3/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
ESR1 P03372 1/20 0.33
TP53 P04637 1/20 0.33
PGR P06401 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
AR P10275 1/20 0.33
MAPT P10636 1/20 0.33
DRD1 P21728 1/20 0.33
PTGS1 P23219 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9359263 0.75 SHBG (0.39) SHBGCYP3A4CYP2D6HIF1ANPC1
SCHEMBL11216918 0.70 CYP3A4 (0.35) SHBGCYP3A4CYP2D6HIF1ASMN1; SMN2
SCHEMBL32664685 0.69 SHBG (0.31) SHBG
SCHEMBL2439208 0.69 SMN1; SMN2 (0.36) SHBGCYP3A4CYP2D6HIF1AGPR84
SCHEMBL2456413 0.68 SNCA (0.43) SHBGCYP3A4CYP2D6HIF1ANPC1
SCHEMBL29504844 0.68 SNCA (0.43) SHBGCYP3A4CYP2D6HIF1ANPC1
SCHEMBL1849037 0.68 CNR2 (0.39)
SCHEMBL2435605 0.66 SMN1; SMN2 (0.36) SHBGCYP3A4CYP2D6HIF1AGPR84
SCHEMBL21346938 0.63 SHBG (0.44) SHBGCYP3A4CYP2D6HIF1ARAB9A
SCHEMBL1718554 0.63 NOX1 (0.54) SHBGCYP3A4NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5579913-A PACKAGING; WATERPROOFING, TRANSPARENT, HIGH MODULUS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-12-03 US disclosed