Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RIOK2 | Q9BVS4 | 5/20 | 0.45 |
| ▸ | CACNA1I | Q9P0X4 | 6/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 6/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 5/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.40 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8988044 | 0.91 | MAPK10 (0.44) | MAPK10SMN1; SMN2ALDH1A1L3MBTL1RIOK2 | |
| SCHEMBL8987852 | 0.90 | SMN1; SMN2 (0.47) | MAPK10SMN1; SMN2ALDH1A1L3MBTL1RIOK2 | |
| SCHEMBL8987736 | 0.89 | SMN1; SMN2 (0.44) | MAPK10SMN1; SMN2ALDH1A1L3MBTL1RIOK2 | |
| SCHEMBL8987985 | 0.89 | MAPK10 (0.47) | MAPK10SMN1; SMN2ALDH1A1L3MBTL1RIOK2 | |
| SCHEMBL8988013 | 0.87 | RIOK2 (0.48) | MAPK10SMN1; SMN2ALDH1A1L3MBTL1RIOK2 | |
| SCHEMBL8987716 | 0.86 | MAPK10 (0.50) | MAPK10SMN1; SMN2ALDH1A1L3MBTL1RIOK2 | |
| SCHEMBL8987881 | 0.86 | SMN1; SMN2 (0.45) | MAPK10SMN1; SMN2ALDH1A1L3MBTL1RIOK2 | |
| SCHEMBL8987842 | 0.85 | SMN1; SMN2 (0.56) | MAPK10SMN1; SMN2ALDH1A1L3MBTL1RIOK2 | |
| SCHEMBL8988094 | 0.84 | MAPK10 (0.46) | MAPK10SMN1; SMN2ALDH1A1L3MBTL1RIOK2 | |
| SCHEMBL8987778 | 0.83 | CACNA1H (0.51) | MAPK10SMN1; SMN2ALDH1A1L3MBTL1RIOK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556859-A | N-(4-pyrimidinyl)amide pesticides | DOWELANCO (US) | 1996-09-17 | — | — | US | disclosed |